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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39605-1
Short code
Goose Feather IgE/IgE total %
Synonyms
Goose Feather IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens (substances like pollen, dust, or certain foods) or parasitic infections. While IgE is normally present in small amounts, higher levels can signal an allergic reaction or an overactive immune response.

Why might this test be ordered?

Your healthcare provider may recommend this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that suggest allergies. It may also be used to diagnose conditions like asthma, eczema, or certain parasitic infections.

How is the test performed?

A small blood sample is taken from a vein in your arm. The blood is then sent to a lab where it is analyzed to measure the total IgE levels using an immunoassay method.

What do my results mean?

Results are not typically provided as a single numeric range, as IgE levels can vary widely depending on age, health status, and specific conditions. Elevated IgE levels may indicate allergies or immune-related conditions, while normal or low levels may suggest no active allergic response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Immunoglobulin E

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are often linked to allergic reactions to environmental triggers (e.g., pollen, pet dander) or specific foods. They can also be seen in conditions like asthma, eczema, or parasitic infections.
What if my IgE levels are normal?
Normal IgE levels do not definitively rule out allergies. Other tests or clinical evaluation may be needed to diagnose allergies or related conditions. Your healthcare provider will consider your symptoms and medical history.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, underlying health conditions, and treatments like allergy medications or immunotherapy. Regular monitoring may be recommended if you have ongoing symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy