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Serum/Plasma Creatinine Concentration (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check: High levels may signal kidney problems; low levels could indicate dehydration or other conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7450-0
Short code
Goosefoot BasoBnd Ab Qn
Synonyms
Goosefoot BasoBnd Ab Qn
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
lhr
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is naturally filtered out of your blood by your kidneys. Your body produces creatinine at a fairly steady rate, so levels can reflect how well your kidneys are working. This test is often used to monitor kidney health, especially in people with risk factors like diabetes, high blood pressure, or a family history of kidney disease.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw (serum/plasma) or urine sample collected, depending on the specific test ordered. If you’re taking certain medications or have a history of kidney issues, let your healthcare provider know before the test.

Common Reasons for Testing

Doctors may order creatinine tests to check for kidney problems, monitor chronic conditions like diabetes or heart disease, evaluate symptoms such as swelling, fatigue, or changes in urine output, or assess the effects of medications that can affect kidney function.

What the Results Mean

Results are typically compared to a reference range provided by your lab. High creatinine levels may indicate reduced kidney function, while very low levels could suggest dehydration or other health issues. Your doctor will interpret results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated creatinine levels often signal impaired kidney function, which can lead to complications like fluid buildup, electrolyte imbalances, or even kidney failure if untreated. Regular monitoring helps detect problems early and allows for timely medical intervention. Low levels may raise concerns about dehydration or other metabolic issues, so follow-up with your healthcare provider is important.

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition. People without kidney issues may get this test as part of routine check-ups every few years. Those with diabetes, high blood pressure, or kidney disease may need it more often, such as every 6 months or annually, as directed by your doctor.
What can affect my creatinine levels?
Several factors can influence creatinine levels, including muscle mass (higher muscle = higher creatinine), dehydration or fluid overload, certain medications (like NSAIDs or contrast dyes), and kidney-related conditions. Your doctor will consider these factors when reviewing your results.
Do I need to fast before this test?
No fasting is required for a creatinine test. However, if you’re having blood drawn, avoid eating or drinking for a short time before the procedure to reduce discomfort. If you’re having a urine test, follow any specific instructions your doctor provides, such as collecting a 24-hour urine sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy