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Nucleic Acid Detection in Blood by Probe-Based Molecular Assay (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of specific genetic material (DNA) in your blood using a molecular probe. It helps identify certain infections or genetic conditions.

Quick summary

["This test detects DNA from pathogens or genetic markers in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93389-5
Short code
GP bact DNA Bld Pos Ql NAA+probe
Synonyms
GP bact DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a specialized probe to detect DNA fragments from bacteria or viruses that may be present in your blood. It does not measure specific quantities but confirms whether the target genetic material is present or absent.

How the Test Works

Your blood sample is analyzed using a molecular technique that amplifies and identifies specific DNA sequences. The probe binds to these sequences if they are present, indicating a positive result for the targeted pathogen or genetic marker.

Common Uses

This test may be used to screen for infections such as bacterial endocarditis (infection of heart valves), sepsis, or other bloodborne infections where DNA evidence is sought. It can also be used in research or specialized diagnostic contexts to detect genetic markers.

Sample Collection and Preparation

A small blood sample is drawn from a vein, typically in your arm. The sample is then processed and prepared for molecular analysis in a laboratory setting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why might I need this test?
Your healthcare provider may recommend this test if you have symptoms of infection (such as fever, chills, or unusual fatigue) or if you are at risk for certain bloodborne infections. It may also be used in research or specialized diagnostic scenarios.
What does a positive result mean?
A positive result indicates that the specific DNA sequence targeted by the probe was detected in your blood. This may suggest the presence of a pathogen or genetic marker, but further testing and clinical evaluation are needed to confirm the diagnosis.
What does a negative result mean?
A negative result means that the specific DNA sequence targeted by the probe was not detected in your blood sample. This does not necessarily rule out an infection or genetic condition, as the test may miss some cases or require additional testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy