Prostate-Specific Antigen (PSA) in Serum or Plasma
This test measures the level of prostate-specific antigen (PSA), a protein produced primarily by the prostate gland. PSA helps doctors assess prostate health, including detecting early signs of prostate cancer or other prostate-related conditions.
["PSA levels can guide discussions about prostate health, but they’re not definitive on their own."]
Key facts at a glance
- LOINC
- 41508-3
- Short code
- Gp B Strep Ag Fld Ql
- Synonyms
- Gp B Strep Ag Fld Ql
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why PSA Testing Matters
PSA is often used as part of a screening process for prostate cancer, especially in men at higher risk. It can also help monitor treatment progress or detect changes in prostate health over time. However, PSA alone isn’t enough to diagnose cancer—it can also rise in other conditions like benign prostatic hyperplasia (BPH) or urinary tract infections.
What to Expect During Testing
A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. Results are typically available within a few days. If your PSA level is elevated, your doctor may recommend further testing or follow-up.
Possible Causes of Elevated PSA
High PSA levels can be caused by prostate cancer, but they may also appear in conditions like an enlarged prostate, inflammation, infection, or recent ejaculation. Age, obesity, or certain medications can also affect PSA levels.
What Your Results Mean
Your PSA result is usually discussed alongside other factors, such as your age, symptoms, and family history. A doctor will interpret results in the context of your overall health. Very low PSA levels might raise concerns about prostate issues, while very high levels may warrant further investigation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
PSA Level
Frequently asked questions
What might cause my PSA level to be higher than expected?
How often should I get a PSA test?
Can lifestyle changes affect PSA levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy