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Genomic DNA from Lower Respiratory Tract (e.g., sputum or bronchial wash) – Probe-Based Assay

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific genetic material in your respiratory tract, often used to detect infections or genetic conditions that may affect lung health.

Quick summary

["Helps identify possible genetic causes of lung-related issues or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94368-8
Short code
Gp B Strep DNA Lower resp Ql NAA+probe
Synonyms
Gp B Strep DNA Lower resp Ql NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test analyzes DNA from cells in your lower respiratory tract, such as those collected from sputum or bronchial secretions. It uses a specialized probe to detect specific genetic sequences, which may indicate the presence of pathogens (like certain viruses or bacteria) or genetic mutations linked to lung disorders.

Why It’s Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent cough, shortness of breath, or if you’re at higher risk for lung infections or genetic lung diseases. It can also be used in research or specialized diagnostic settings.

Sample Collection and Preparation

A sample of respiratory secretions (e.g., sputum or bronchial wash) is collected, typically by coughing into a container or through a bronchoscopy. The sample is then processed to extract DNA for testing.

What to Expect Before the Test

No special preparation is usually needed, but you may need to avoid certain medications (like antibiotics) that could interfere with results. Follow your provider’s instructions for sample collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test can help confirm or rule out genetic infections (e.g., certain viral or bacterial DNA) or identify genetic predispositions to lung diseases. It may also assist in monitoring treatment responses or guiding further diagnostic steps.

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of specific genetic material in your respiratory sample, which may suggest an infection (like a virus or bacteria) or a genetic condition affecting lung health. Your provider will discuss next steps based on the findings.
How long will results take?
Results are typically available within a few days to a couple of weeks, depending on laboratory processing times and complexity of the genetic analysis.
Can I take anything to lower my risk of false positives?
No specific pre-test actions can eliminate false positives, but avoiding recent antibiotic use or other medications that may alter DNA detection can help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy