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Genital Rectal Swab for Nucleic Acid Amplification (NAA) Detection of Human Papillomavirus (HPV) Types

Published: August 9, 2026Updated: August 16, 2026

This test checks for certain types of human papillomavirus (HPV) that may be present in your genital or rectal area. HPV is a common virus that can sometimes cause health issues like warts or long-term changes in cells that may lead to cancer.

Quick summary

["HPV testing helps identify potential risks for certain cancers and guides decisions about follow-up care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91875-5
Short code
Gp B Strep DNA Vag+Rectum Ql NAA+probe
Synonyms
Gp B Strep DNA Vag+Rectum Ql NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unusual vaginal, cervical, or rectal discharge; genital warts; or if you have a history of HPV-related health concerns. It’s also used as part of routine screening for certain populations at higher risk.

How the Test Works

A healthcare provider collects a sample from your genital or rectal area using a special swab. The sample is then tested in a lab to detect specific HPV DNA types linked to higher cancer risks.

What to Expect Before the Test

No special preparation is needed, but you may want to avoid sexual activity or douching 24 hours before the test. Wear comfortable clothing and bring any medications you’re currently taking.

What to Expect During the Test

The test is quick and usually painless. You may feel a slight discomfort or mild pressure, but it shouldn’t cause significant pain. The provider will explain the procedure before starting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HPV is the most common sexually transmitted infection globally. Certain HPV types can cause precancerous changes in cells or lead to cancers like cervical, vaginal, vulvar, anal, or penile cancer. Early detection helps manage risk and prevents complications. This test is particularly important for people at higher risk, such as those with weakened immune systems or a history of HPV-related cancers.

Short name

HPV Genital Rectal Swab Test

Frequently asked questions

How soon will I get my results?
Results are typically available within 1–2 weeks, depending on lab processing times. Your healthcare provider will contact you directly with the results and any next steps.
What does a positive result mean?
A positive result means HPV DNA was found in your sample. This doesn’t always mean you have cancer now, but it increases your risk. Follow-up testing or monitoring may be recommended based on your provider’s guidance.
Can I still have sex after the test?
Yes, you can resume sexual activity as usual unless your provider advises otherwise. Avoid douching or sexual activity for 24 hours before the test to ensure an accurate sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy