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Glutamate Oxaloacetate Transaminase (GOT) in Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the activity of an enzyme called glutamate oxaloacetate transaminase (GOT), which helps assess liver function and detect potential liver damage.

Quick summary

["GOT helps doctors check for liver issues, including inflammation or injury."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
44050-3
Short code
GPI RBC-cCnt
Synonyms
GPI RBC-cCnt
Category
glucose
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

GOT is an enzyme found in the liver, heart, muscle, and other tissues. When liver cells are damaged, GOT leaks into the bloodstream, raising its levels. This test helps identify conditions like hepatitis, liver disease, or alcohol-related liver damage.

Why Might I Need This Test?

Your healthcare provider may order this test if you have symptoms like jaundice (yellow skin), fatigue, abdominal pain, or if they suspect liver problems from conditions like hepatitis, cirrhosis, or exposure to toxins.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 12 hours before the blood draw if your doctor specifies it. Bring any medications or supplements you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick and generally painless. The blood sample is then sent to a lab for analysis.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated GOT levels often indicate liver damage or disease, but they can also be raised in other conditions like heart attacks, muscle injuries, or certain infections. While GOT alone isn’t diagnostic, it’s often used alongside other tests to guide treatment decisions.

Short name

AST (Serum)

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I eat or drink before this test?
Follow your doctor’s instructions—some tests require fasting, while others do not. If fasting is needed, avoid food and liquids (except water) for 12 hours before the test unless directed otherwise.
What if my GOT level is higher than expected?
If your GOT level is elevated, your doctor may recommend further testing to identify the cause, such as liver function tests, imaging, or a biopsy. Treatment depends on the underlying condition, which your provider will address with you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy