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Post-transplant immune function assessment (e.g., donor-specific antibody monitoring or graft-specific immune response)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates how well your immune system interacts with your donated organ after transplant, often to check for rejection or immune response to the graft.

Quick summary

["This test helps doctors monitor long-term graft health and adjust treatment if needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68352-4
Short code
GRAFTFUNCTIONINGATDEATH
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

After receiving an organ transplant, your body’s immune system may still react to the new organ. This test helps track whether your immune response is normal or if it’s causing problems like rejection. It may also check for antibodies that could harm the graft or trigger immune reactions.

What to Expect Before the Test

No special preparation is needed unless instructed by your healthcare team. Blood is drawn from a vein, similar to other routine blood tests. The test may involve checking for specific antibodies or immune markers related to the transplanted organ.

What the Results Mean

Results may show whether your immune system is recognizing the graft as foreign (potentially causing rejection) or if it’s adapting normally. High levels of certain markers might indicate an immune response that needs medical attention.

Common Causes for This Test

Doctors order this test if you’re at risk for transplant rejection, have symptoms like organ swelling or poor function, or if you’re on immune-suppressing medications that require monitoring.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for preventing graft failure by identifying early signs of immune rejection or complications. It helps tailor treatment to protect the transplanted organ while balancing immune safety.

Frequently asked questions

What does a positive or abnormal result mean for my graft health?
An abnormal result may signal an immune response that could harm the graft. Your doctor will review the results with you and adjust medications or monitoring plans as needed to support your graft’s health.
How often will I need this test?
Frequency depends on your transplant type, health, and medications. Your healthcare team will schedule follow-up tests based on your individual care plan.
Can lifestyle changes affect this test results?
While diet, exercise, and avoiding infections can support overall health, they may indirectly influence immune responses. Always follow your doctor’s guidance for test-related adjustments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy