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Total Protein (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes albumin and other proteins like globulins.

Quick summary

["Your blood protein levels help assess overall health and detect potential issues like kidney disease or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87971-8
Short code
Gram Stn Amn
Synonyms
Gram Stn Amn
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
gram-stain
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why It’s Done

Doctors may order a total protein test to check for conditions affecting protein production, absorption, or kidney function. It can also help diagnose diseases like liver problems, infections, or certain cancers.

What to Expect

A small blood sample is taken from your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test is quick and doesn’t require special preparation.

Normal vs. Abnormal Results

While reference ranges vary by lab, lower than expected protein levels might suggest malnutrition, liver disease, or kidney problems. Higher levels could indicate conditions like multiple myeloma or severe dehydration.

Common Conditions Monitored

This test is often used alongside other blood tests to monitor conditions like chronic kidney disease, liver disorders, or immune system issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Protein

Frequently asked questions

What does my total protein test result mean?
Your result will be compared to standard reference values. If it’s outside the expected range, your doctor may recommend further tests or adjustments to your treatment plan.
Can I eat or drink before this test?
No special preparation is needed. However, if you’re on certain medications, let your healthcare provider know before your test.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy