Granulocyte Count in Cerebrospinal Fluid (CSF) by Microscopic Examination

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like headaches, neck stiffness, fever, confusion, or signs of a brain or spinal cord infection. It’s also used to monitor conditions like meningitis, encephalitis, or other neurological disorders that affect white blood cell counts in CSF.

What to Expect Before the Test

No special preparation is needed. You may receive a local anesthetic to numb the area where the fluid is collected. The test involves a small needle inserted into your spine to draw CSF, which is then examined under a microscope.

What the Test Results Mean

The results show the number of granulocytes (a type of white blood cell) in the CSF. High levels may suggest infection, inflammation, or other conditions affecting the central nervous system. Your provider will interpret the results in the context of your symptoms and medical history.

Common Conditions Affecting Results

Elevated granulocyte counts in CSF are often seen in infections (like bacterial or fungal meningitis), inflammatory conditions (such as multiple sclerosis or certain brain tumors), or after trauma to the spine or brain.