Serum or Plasma Protein Electrophoresis (Qualitative) with Bromocresol Green Staining
This test measures the distribution of different protein fractions in your blood, often used to identify abnormalities in protein levels that may signal conditions like multiple myeloma, liver disease, or kidney problems.
["Helps detect protein imbalances that could indicate serious health concerns."]
Key facts at a glance
- LOINC
- 88001-3
- Short code
- Gram Stn DiafP
- Synonyms
- Gram Stn DiafP
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 10
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- gram-stain
- CPT
- 82105
- SNOMED
- 394971007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test uses electrophoresis to separate blood proteins into bands based on size and charge. Bromocresol Green dye binds to specific protein groups, allowing for qualitative assessment of albumin, alpha-globulins, beta-globulins, and gamma-globulins. This helps identify patterns that may suggest underlying conditions.
How the Test Works
A small blood sample is drawn and placed in a gel or medium. An electric current is applied, causing proteins to migrate toward the positive electrode. The dye stains different protein groups distinctly, creating visible bands that can be analyzed.
Common Conditions Monitored
This test is primarily used as a screening tool for conditions affecting protein synthesis or breakdown, such as multiple myeloma (cancer of plasma cells), liver disease, kidney disease, or certain autoimmune disorders.
When You Might Need This Test
Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, frequent infections, or if you have a history of conditions that alter protein levels.
Reference range
Normal: <10 ng/mLN/A
No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis (BCG)
Frequently asked questions
Why might my doctor want to check this protein pattern?
What do abnormal results mean?
How is this test different from a standard protein test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy