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Skin Gram Stain (Microscopic Examination of Skin Specimen)

Published: August 9, 2026Updated: August 16, 2026

This test examines a sample of your skin under a microscope to identify bacteria, fungi, or other microorganisms that may be causing an infection or skin condition.

Quick summary

["A microscopic look at your skin’s microbes can help diagnose infections or abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90296-5
Short code
Gram Stn Skin
Synonyms
Gram Stn Skin
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
gram-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a Skin Gram Stain Used For?

Skin Gram stains are primarily used to detect and identify organisms responsible for skin infections, such as bacterial or fungal infections. This can help determine the appropriate treatment, whether it involves antibiotics, antifungals, or other therapies.

How Is the Test Performed?

A small sample of your skin is collected, usually through swabbing or scraping, and then prepared on a microscope slide. The sample is stained to highlight different microorganisms, which are then observed under a microscope by a healthcare professional.

Preparation and Care Before the Test

No special preparation is needed for this test. You may be asked to wash the affected area gently with soap and water before the sample is collected to ensure a clean sample. Avoid applying lotions, creams, or ointments to the area.

What Happens During the Test?

The healthcare provider will gently swab or scrape a small amount of skin from the affected area. The sample is then sent to the lab for staining and microscopic examination. Results are typically available within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing infections such as cellulitis, impetigo, or fungal skin infections. Identifying the specific microorganism helps guide treatment decisions, ensuring targeted and effective therapy to clear the infection and prevent complications.

Short name

Skin Gram Stain

Frequently asked questions

Why might I need a skin Gram stain?
You may need this test if you have symptoms like redness, swelling, pus, or an unusual rash that doesn’t improve with over-the-counter treatments, or if you have a chronic skin condition that requires monitoring for infections.
How long does it take to get the results of this test?
Results are usually available within 2 to 5 business days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I take anything by mouth before the test?
Yes, you can take your usual medications as directed by your healthcare provider. Avoid applying any topical medications to the test site unless instructed otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy