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Total Serum Protein by Bromocresol Green (BCG) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes albumin and other proteins like globulins. It helps assess overall protein status and potential issues like malnutrition or kidney problems.

Quick summary

["A simple blood test to check for protein balance in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87973-4
Short code
Gram Stn Smn
Synonyms
Gram Stn Smn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
gram-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your body needs proteins to build and repair tissues, fight infections, and maintain healthy blood. Low protein levels may signal conditions like severe malnutrition, kidney disease, or liver problems, while high levels might indicate dehydration or certain inflammatory diseases.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic evaluation. Bring any medications you’re currently taking to your doctor’s office.

Common Conditions Monitored

This test is often used to monitor conditions like chronic kidney disease, liver disease, or severe infections. It can also help diagnose or track protein-losing syndromes, where the body loses protein through urine or stool.

How the Test Works

A small blood sample is drawn from your arm. The serum is then tested using bromocresol green dye, which binds to proteins. The color change is measured to determine the protein concentration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Screening

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–2 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I eat or drink anything before this test?
Most often, fasting is not required, but check with your doctor or lab technician about any specific instructions for your situation. If fasting is advised, avoid food and liquids (except water) for 8–12 hours before the test.
What does a low or high protein result mean?
A low protein result may signal conditions like malnutrition, kidney disease, or liver dysfunction. A high result could indicate dehydration, but it may also be part of a broader evaluation for inflammation or other health concerns. Your doctor will interpret results in the context of your medical history and other tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy