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Total Serum Protein by Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum using electrophoresis, a method that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like infections, kidney disease, or certain cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14363-6
Short code
Gram Stn Snv
Synonyms
Gram Stn Snv
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
gram-stain
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins into five main zones: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins (antibodies). Each zone reflects different protein functions and potential health issues.

Why It’s Ordered

Your doctor may order this test to diagnose or monitor conditions such as multiple myeloma, lymphoma, liver disease, kidney problems, or chronic infections.

Sample Preparation

A blood sample is drawn, and serum is separated for testing. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.

Turnaround Time

Results are typically available within 24 to 48 hours, depending on lab processing and your healthcare provider’s workflow.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Protein Electrophoresis

Frequently asked questions

Abnormal protein patterns, such as elevated or low levels in specific zones, may indicate underlying health problems that require further medical evaluation.
This test can help detect conditions like hypoalbuminemia (low albumin), which may cause swelling or poor wound healing, or elevated gamma globulins, which could signal autoimmune diseases or infections.
How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, but timing can vary based on lab procedures and your healthcare provider’s schedule. Your doctor will discuss results with you.
Can I eat or drink before this test?
No special diet is required for this test, but always follow your doctor’s instructions. If fasting is advised for another reason, they’ll let you know.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy