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Granulocyte Count (Manual Differential Blood Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of granulocytes (a type of white blood cell) in your blood, often done manually for detailed analysis.

Quick summary

["Granulocytes help fight infections and inflammation; this test helps assess immune function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31160-5
Short code
Granulocytes NFr Bld Manual
Synonyms
Granulocytes NFr Bld Manual
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate immune health, diagnose infections, or monitor conditions like leukemia, autoimmune diseases, or chronic inflammation. Granulocytes are part of the body’s first line of defense against bacteria and fungi.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your provider know—they can help.

What the Test Results Mean

Results show the absolute count of granulocytes (e.g., per microliter of blood). Low counts may indicate infection, bone marrow issues, or immune disorders; high counts could signal chronic inflammation or other conditions.

Common Conditions Monitored

This test is often used to monitor patients with: - Infections (e.g., bacterial or fungal), - Blood cancers (e.g., leukemia), - Autoimmune diseases (e.g., rheumatoid arthritis), or - Chronic inflammatory conditions (e.g., Crohn’s disease).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Granulocyte Count

Frequently asked questions

What causes granulocyte counts to be low?
Low granulocyte counts can result from infections, certain medications, autoimmune diseases, or bone marrow disorders. If you notice frequent infections or unexplained fatigue, discuss this with your provider.
How often should I get this test?
Frequency depends on your condition. Your provider will schedule follow-up tests based on your treatment plan, symptoms, or ongoing health needs.
Can diet or supplements affect granulocyte counts?
Dietary changes alone rarely affect granulocyte counts, but certain supplements (e.g., high-dose vitamins) or medications may influence white blood cell levels. Always check with your provider before starting new supplements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy