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Absolute Neutrophil Count (ANC) from Complete Blood Count (CBC) with Differential

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and are part of your immune system.

Quick summary

["Neutrophils protect your body from bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14773-6
Short code
Granulocytes NFr Bronch Manual
Synonyms
Granulocytes NFr Bronch Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Neutrophils Do in Your Body

Neutrophils are a key part of your immune system. They’re the most common type of white blood cell and play a critical role in defending your body against bacterial infections. When you have an infection, your body releases signals to increase neutrophil production, helping you fight off germs. However, too many or too few neutrophils can indicate health problems.

How This Test Works

Your blood sample is analyzed to count the absolute number of neutrophils. This is typically done as part of a complete blood count (CBC), which also includes other blood cell types. The test may be performed using automated blood cell counters or manual differential staining methods.

When You Might Need This Test

Doctors may order this test if you have symptoms like frequent infections, fever, fatigue, or if you’re recovering from surgery, chemotherapy, or a serious illness. It can also be used to monitor conditions like leukemia, autoimmune diseases, or infections.

Possible Results and What They Mean

Results are usually reported as an absolute count (number of neutrophils per microliter of blood). Low neutrophil counts (neutropenia) may suggest immune suppression, while very high counts (neutrophilia) could indicate infection, inflammation, or other conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low neutrophil counts can increase your risk of severe infections, especially with bacteria. This is often seen in conditions like chemotherapy-induced neutropenia, autoimmune diseases, or certain blood disorders. High neutrophil counts may signal acute infections, stress, or inflammatory processes. Your doctor will interpret results in the context of your overall health and symptoms.

Short name

Neutrophil Count

Frequently asked questions

Why might my doctor ask for this test?
Your doctor may request this test to check your immune response, especially if you’re at risk for infections due to medical treatments, chronic conditions, or recent illness. It helps monitor how well your body is fighting off germs.
What do my neutrophil results mean?
Your results will be compared to standard ranges for your age and health. A lower-than-normal count may mean your immune system isn’t working as well as it should, while a higher-than-normal count could signal an infection or other health issue. Your doctor will explain what your specific results mean for you.
Can I prepare for this test?
No special preparation is needed for this test. You may have a simple blood draw, often done in a doctor’s office or lab. If you’re on certain medications or have a history of bleeding disorders, let your healthcare provider know before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy