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Granulocyte Differential Count (Manual Differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the percentage of white blood cells that belong to the granulocyte group (neutrophils, eosinophils, and basophils) in your blood. It’s done manually by a lab technician to provide detailed cell counts.

Quick summary

["Granulocytes help fight infections, and their count can indicate health risks or conditions like infections, inflammation, or blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14330-5
Short code
Granulocytes NFr Stl Manual
Synonyms
Granulocytes NFr Stl Manual
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions such as infections (like bacterial or fungal), autoimmune diseases, blood cancers, or reactions to medications. It can also help track how well treatments are working.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. The process takes only a few minutes, and you can return to your normal activities afterward.

What the Results Mean

The test provides the proportion of granulocytes (neutrophils, eosinophils, and basophils) among all white blood cells. Abnormal levels can signal infections, allergies, or other health issues. Your doctor will interpret the results in the context of your symptoms and medical history.

Common Conditions Linked to Granulocyte Levels

High granulocyte counts may indicate infections, inflammation, or stress. Low granulocyte counts could suggest immune deficiencies, certain cancers, or blood disorders. Always discuss your results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Manual WBC Differential (Granulocytes)

Frequently asked questions

How long does it take to get the results of this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your doctor will contact you with the final report.
Can I eat or drink before this test?
No special diet or fasting is required for this test. However, inform your doctor about any medications or supplements you’re taking, as they may affect blood counts.
Is there any risk or discomfort with this test?
The most common discomfort is a slight bruise or pinch at the injection site. Rarely, there may be mild swelling or bleeding. Most people tolerate the procedure well.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy