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Total Grapefruit Juice Content (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of grapefruit juice components in your blood, often checked if grapefruit interactions with medications are suspected.

Quick summary

["Grapefruit juice can affect how your body processes certain medications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43587-5
Short code
Grape IgE/IgE total %
Synonyms
Grape IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’ve been taking medications that grapefruit juice could interact with, such as blood pressure drugs, cholesterol-lowering drugs, or certain heart medications. It helps assess whether grapefruit juice is altering how your body absorbs these drugs.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’ve consumed grapefruit juice recently, mention it to your provider, as it may affect results.

What the Results Mean

Results indicate the concentration of grapefruit juice metabolites in your blood. High levels may suggest recent grapefruit juice intake or potential drug interactions. Your provider will interpret results in the context of your medications and symptoms.

Common Causes of Abnormal Results

Abnormally high levels may occur if you’ve consumed grapefruit juice within hours of testing or if you’re taking medications that grapefruit juice interacts with. Low levels may indicate normal metabolism or absence of grapefruit juice exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Grapefruit Juice Level

Frequently asked questions

Could grapefruit juice consumption affect this test result?
Yes, grapefruit juice consumption can significantly alter results. If you’ve eaten grapefruit or drank juice within a few hours of your blood draw, your results may reflect those effects. Always inform your provider about recent grapefruit exposure.
What does a positive result mean for my health?
A positive result (high grapefruit juice metabolites) suggests grapefruit juice may be interfering with how your body processes certain medications. Your provider will review your medication list and symptoms to determine if adjustments are needed.
Is this test painful or uncomfortable?
The blood draw is mild discomfort, similar to a routine lab test. Most people tolerate it well. If you’re anxious, let your provider know so they can prepare you accordingly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy