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Total Immunoglobulin E (IgE) Level in Serum (Allergen-Specific Mix)

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to multiple common allergens, including pollen, dust mites, pet dander, and mold, by detecting IgE antibodies in your blood.

Quick summary

["Assesses specific allergic sensitivities to common environmental triggers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61204-4
Short code
Grass Allerg Mix2 IgE/IgE total %
Synonyms
Grass Allerg Mix2 IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

IgE antibodies are part of your immune system’s defense against allergens. When your body encounters an allergen, it may produce IgE to help identify and respond to it. This test checks for elevated levels of IgE directed toward specific allergens, which can indicate an allergic reaction risk.

Why It’s Ordered

Your healthcare provider may recommend this test if you suspect allergies to environmental triggers, have symptoms like sneezing, itching, or skin reactions, or if you’ve had a negative skin test but suspect allergies persist.

Preparation and Sample Collection

No special preparation is needed. A blood sample will be taken from a vein in your arm by a healthcare professional. The blood is processed to separate serum for testing.

Test Results and Interpretation

Results are reported as positive or negative for each allergen in the mix. Elevated IgE levels for specific allergens suggest a heightened sensitivity, but results alone do not confirm a diagnosis of allergy. They are often used alongside other tests or clinical findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Mix Test

Frequently asked questions

What does elevated IgE mean?
Elevated IgE levels for certain allergens may indicate an allergic reaction risk. However, IgE alone does not diagnose an allergy—it helps guide further evaluation, such as skin prick tests or allergy challenges. Results should be interpreted by a healthcare provider in the context of your symptoms and medical history.
Can this test predict allergies in the future?
No, this test does not predict future allergic reactions. It measures current IgE levels to specific allergens and helps assess past or existing sensitivities.
How often should I get this test?
The frequency depends on your symptoms and healthcare provider’s recommendations. Some people may need retesting if symptoms change or if allergies are suspected after exposure to new allergens.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy