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C-reactive protein (CRP) measured by high-performance liquid chromatography (HPLC) or similar quantitative method in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used alongside other tests to monitor conditions like infections, autoimmune diseases, or heart disease risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87078-2
Short code
Guided Abd PC drn+cath place
Synonyms
Guided Abd PC drn+cath place
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for signs of inflammation, monitor chronic conditions (such as rheumatoid arthritis or heart disease), or evaluate symptoms like fever, joint pain, or swelling. It can also help determine if an infection is present or if your body is reacting to an injury.

What to Expect Before the Test

No special preparation is needed for this test. You’ll typically have a small needle inserted into your arm to draw a blood sample. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Higher-than-normal CRP levels often indicate inflammation, but they can also be elevated due to other factors like stress, certain medications, or recent illness. Your results will be interpreted by your healthcare provider in the context of your overall health and symptoms.

Common Conditions Monitored

CRP is commonly used to track conditions like inflammatory diseases (e.g., lupus, arthritis), infections (e.g., pneumonia, sepsis), or to assess cardiovascular risk. It’s also sometimes used to monitor treatment responses in certain conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Plasma)

Frequently asked questions

How long does it take to get my CRP results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
You can eat and drink normally before this test unless instructed otherwise. No fasting is required.
Is there any risk or discomfort with this test?
Most people experience only minor discomfort or a slight pinch at the injection site. Rarely, there may be bruising or a small bump. If you have a bleeding disorder or are on blood thinners, let your provider know to reduce risks.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy