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Guided Clinical Luminal Evaluation of Mechanical Luminal Obstruction (GLEMOL)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates how blood flow is affected by narrowing or blockages in blood vessels, using a guided approach to assess mechanical obstruction. It helps determine if a vessel’s lumen (opening) is physically blocked or narrowed, which may impact circulation.

Quick summary

["Assesses vessel blockages that could affect blood flow and circulation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87186-3
Short code
Guided CVC lumen obstr mech thromb
Synonyms
Guided CVC lumen obstr mech thromb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The GLEMOL test measures the **mechanical obstruction index** within blood vessels, specifically evaluating how resistance to blood flow changes when passing through narrowed or obstructed areas. This is done through a specialized imaging or flow-based assessment that quantifies luminal narrowing or blockage severity.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like reduced blood flow (e.g., cold limbs, pain, or fatigue), suspected vascular disease, or if imaging (like an angiogram) suggests mechanical obstruction but further evaluation is needed to confirm or refine findings.

Common Causes

Mechanical obstructions in vessels can arise from conditions such as atherosclerosis (plaque buildup), arterial stenosis (narrowing), or external compression from masses or scars. It may also be used to assess post-surgical or post-intervention vessel patency.

Who Might Need This Test

Patients with suspected vascular disease (e.g., peripheral artery disease), those undergoing vascular procedures, or individuals with unexplained circulation issues may require this test to guide treatment decisions or monitor vessel health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GLEMOL Test

Frequently asked questions

What does the test result mean?
A result indicates the degree of mechanical obstruction in vessels. High obstruction scores may suggest severe narrowing requiring intervention (e.g., angioplasty, stenting), while lower scores may indicate mild obstruction or no significant blockage. Results help tailor treatment plans, such as lifestyle changes, medications, or surgical options.
How is the test performed?
The test typically involves advanced imaging (e.g., intravascular ultrasound or Doppler flow studies) combined with a guided approach to measure resistance to blood flow through narrowed segments. A small catheter or probe is often used to directly assess vessel lumen mechanics.
What are the risks or side effects?
Risks may include minor discomfort during the procedure, temporary bruising, or rare complications like vessel injury. Your provider will discuss risks based on your health status and the specific technique used.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy