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: Guided Soft Tissue Biopsy

Published: August 9, 2026Updated: August 16, 2026

: A guided soft tissue biopsy is a procedure in which a small sample of soft tissue is removed with imaging guidance so it can be examined in a laboratory. It helps your care team determine what is happening in the tissue and plan appropriate care.

Quick summary

[": A guided soft tissue biopsy provides a tissue sample for laboratory evaluation to help diagnose the cause of a soft tissue abnormality."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87016-2
Short code
Guided Soft tiss Bx
Synonyms
Guided Soft tiss Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Is

: This is a tissue sampling procedure, not a blood test. A doctor uses imaging such as ultrasound or CT to guide a needle to a specific area of soft tissue, such as muscle, fat, or connective tissue, and removes a small sample. The sample is then sent to a pathology laboratory for examination.

: Why It May Be Done

: Your care team may recommend this procedure when imaging tests show a lump, mass, or area of abnormal soft tissue that needs to be identified. A biopsy can help distinguish benign changes from infection, inflammation, or other conditions. Your doctor will explain the specific reason it is being recommended for you.

: How to Prepare

: Preparation instructions vary depending on the location of the biopsy and your health history. You may be asked about medicines that affect bleeding, allergies, and prior imaging, and you may need to adjust food or fluid intake before the procedure. Follow the instructions your care team gives you.

: What to Expect

: The procedure is often done on an outpatient basis and may use local numbing medicine. You may feel pressure or brief discomfort during sampling. Afterward, the site is usually checked and you may receive instructions about activity, wound care, and when to expect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: NONE

Frequently asked questions

: How long does it take to get biopsy results?
: Timing varies by laboratory and by the type of testing needed on the sample. Some results are available within a few days, while others may take longer if special studies are required. Ask your care team when to expect your results.
: Is a guided soft tissue biopsy painful?
: Most people tolerate the procedure well, especially with local numbing medicine. You may feel pressure or brief discomfort during the sampling. Tell your care team if you feel pain so they can help keep you comfortable.
: What should I do after the procedure?
: Follow the specific instructions from your care team about wound care, activity, and warning signs to watch for. Contact them if you have increasing pain, bleeding, fever, or other concerns.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy