Pericardial Fluid (Pericardium) Content: Total Protein by Bromocresol Green Method
This test measures the total protein level in fluid collected from around your heart. High protein levels may indicate inflammation, infection, or other conditions affecting the pericardium.
["Protein levels in pericardial fluid can signal underlying heart or pericardial issues that may need medical attention."]
Key facts at a glance
- LOINC
- 87199-6
- Short code
- Guided Unsp region CVC pericath obs rem
- Synonyms
- Guided Unsp region CVC pericath obs rem
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- imaging-modality
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like chest pain, shortness of breath, or signs of fluid buildup around the heart. It helps diagnose conditions such as pericarditis, cardiac tamponade, or other pericardial diseases.
What to Expect Before the Test
No special preparation is needed. The fluid is typically collected through a procedure called pericardiocentesis, where a needle is inserted into the pericardial sac under guidance from imaging (like an ultrasound). You may feel discomfort but should not experience significant pain.
What the Results Mean
Protein levels in pericardial fluid can vary widely depending on the cause. Elevated levels often suggest inflammation, infection, or bleeding into the pericardium. Lower levels may be normal or could indicate other conditions like constrictive pericarditis.
Common Conditions Linked to Abnormal Results
High protein levels may be linked to conditions such as pericarditis (inflammation of the pericardium), cardiac trauma, or malignancies that spread to the pericardium. Low or normal levels may be seen in conditions like constrictive pericarditis or benign pericardial effusion.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Protein in Pericardial Fluid
Short name
Pericardial Protein Test
Frequently asked questions
Will this test hurt?
How long will I have to wait for results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy