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Pericardial Fluid (Pericardium) Content: Total Protein by Bromocresol Green Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total protein level in fluid collected from around your heart. High protein levels may indicate inflammation, infection, or other conditions affecting the pericardium.

Quick summary

["Protein levels in pericardial fluid can signal underlying heart or pericardial issues that may need medical attention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87199-6
Short code
Guided Unsp region CVC pericath obs rem
Synonyms
Guided Unsp region CVC pericath obs rem
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like chest pain, shortness of breath, or signs of fluid buildup around the heart. It helps diagnose conditions such as pericarditis, cardiac tamponade, or other pericardial diseases.

What to Expect Before the Test

No special preparation is needed. The fluid is typically collected through a procedure called pericardiocentesis, where a needle is inserted into the pericardial sac under guidance from imaging (like an ultrasound). You may feel discomfort but should not experience significant pain.

What the Results Mean

Protein levels in pericardial fluid can vary widely depending on the cause. Elevated levels often suggest inflammation, infection, or bleeding into the pericardium. Lower levels may be normal or could indicate other conditions like constrictive pericarditis.

Common Conditions Linked to Abnormal Results

High protein levels may be linked to conditions such as pericarditis (inflammation of the pericardium), cardiac trauma, or malignancies that spread to the pericardium. Low or normal levels may be seen in conditions like constrictive pericarditis or benign pericardial effusion.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Protein in Pericardial Fluid

Short name

Pericardial Protein Test

Frequently asked questions

Will this test hurt?
The procedure itself may cause mild discomfort or bruising, but most patients report it as tolerable. Pain is usually managed with over-the-counter pain relievers if needed. Always follow your healthcare provider’s instructions for post-procedure care.
How long will I have to wait for results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
No dietary restrictions apply to this test. However, if fluid is collected for other reasons (e.g., diagnostic imaging), follow any specific instructions your doctor provides.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy