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Urine Ductal Brush Cytology (Guided Ureteral Brush Cytology)

Published: August 9, 2026Updated: August 16, 2026

This test involves collecting cells from the ureter—a tube that carries urine from the kidneys to the bladder—using a guided brush. It helps detect abnormal cells that may suggest conditions like kidney stones, tumors, or other urinary tract issues.

Quick summary

["This test may be used to investigate unexplained symptoms or abnormalities found during other diagnostic tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87043-6
Short code
Guided Ureter Bx
Synonyms
Guided Ureter Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is the Purpose of This Test?

Ureteral brush cytology is often performed when doctors suspect a problem in the ureter, such as blockages, tumors, or infections. It may also be used after procedures like ureteral stents to check for complications or residual issues. Your healthcare provider will explain why this test is needed for your specific situation.

How Is the Test Performed?

During the procedure, a thin, flexible tube with a brush tip is guided through the ureter using imaging (like a CT or X-ray) to reach the area of concern. Cells collected from the brush are then examined under a microscope to identify any abnormal cells.

What Are Common Symptoms That Might Lead to This Test?

You may undergo this test if you experience symptoms like persistent pain in the side or back (flank pain), blood in urine, unexplained weight loss, or if imaging tests (like a CT scan) show suspicious findings in the ureter.

What Should You Expect Before, During, and After the Test?

Before the test, you may be asked to drink extra fluids to help flush out the urinary system. During the procedure, you’ll likely feel mild pressure or discomfort but may be given sedation if needed. Afterward, you may experience mild soreness or discomfort in the side where the procedure was done. Follow-up care will depend on your provider’s findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Ureteral Brush Cytology

Frequently asked questions

What Does the Test Result Mean?
The results will be reviewed by a pathologist or cytologist. Normal results mean no abnormal cells were found. Abnormal results may indicate conditions like kidney stones, tumors, or inflammation. Your doctor will discuss the results in detail and may recommend further testing or treatment based on the findings.
How Often Should This Test Be Done?
This test is typically done as a one-time diagnostic procedure when symptoms or imaging suggest a specific issue. It is not a routine screening test unless recommended by your healthcare provider for your condition.
Will This Test Affect My Daily Activities?
Most people can return to normal daily activities immediately after the procedure, though you may need to avoid strenuous activity for a short time. If you experience severe pain, bleeding, or other concerning symptoms, contact your healthcare provider right away.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy