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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61261-4
Short code
Gum-Tree IgE/IgE total %
Synonyms
Gum-Tree IgE/IgE total %
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sneezing, itching, rashes, or breathing difficulties that suggest allergies. It may also be used to diagnose conditions like asthma, hay fever, or other allergic reactions, or to check for immune system responses to infections or parasites.

What to Expect During the Test

A blood sample will be taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause much discomfort. The blood is then sent to a lab for analysis.

What the Results Mean

IgE levels can vary widely among individuals. High levels may indicate allergies, asthma, or other allergic conditions. Low levels might suggest a reduced immune response to allergens or parasites. Consult your healthcare provider for interpretation of your specific results.

Common Reasons for Testing

This test is often used to confirm allergies to specific substances like foods, pollen, pet dander, or medications. It can also help diagnose conditions such as atopic dermatitis, chronic urticaria, or certain parasitic infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

What are the normal IgE levels?
Normal IgE levels can vary and are not strictly defined by a single range. Elevated IgE levels often correlate with allergic conditions, while very low levels may indicate a reduced allergic response or other immune-related conditions. Your doctor will evaluate your results in the context of your symptoms and medical history.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on factors like age, exposure to allergens, underlying health conditions, and treatments. Regular monitoring may be necessary if you have ongoing symptoms or conditions that affect your immune response.
Is there anything I should avoid before this test?
Generally, no special preparations are needed for this test. However, if you are taking medications that might affect your immune response, inform your healthcare provider before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy