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Serum or Plasma *Alpha-1 Antitrypsin* Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of alpha-1 antitrypsin (A1AT) in your blood, a protein that helps protect your lungs and liver from damage caused by enzymes.

Quick summary

["Alpha-1 antitrypsin levels help identify potential lung or liver conditions linked to genetic mutations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88902-2
Short code
HAdV Ur Ql Cult
Synonyms
HAdV Ur Ql Cult
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like chronic cough, shortness of breath, or liver issues, or if you have a family history of alpha-1 antitrypsin deficiency—a genetic condition that can affect lung or liver health over time.

What to Expect Before the Test

No special preparation is needed. You may fast before the test, but your provider will confirm if fasting is required. Bring any medications you’re currently taking, as some may affect results.

How the Test Works

A blood sample is drawn from a vein in your arm. The sample is sent to a lab, where it is analyzed using an immunoassay method to measure the concentration of alpha-1 antitrypsin protein.

What the Results Mean

Results are compared to a standard range for healthy individuals. Low levels may indicate alpha-1 antitrypsin deficiency, while normal or high levels suggest no immediate concern unless symptoms exist.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha-1 Antitrypsin (Serum/Plasma)

Frequently asked questions

What causes abnormal alpha-1 antitrypsin levels?
Abnormal levels are often linked to genetic mutations passed down through families. Rarely, conditions like liver disease or certain infections can temporarily alter levels, but genetic testing is needed to confirm deficiency.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your provider will discuss them with you during your follow-up visit.
Can lifestyle changes affect alpha-1 antitrypsin test results?
No, lifestyle factors like diet or exercise do not directly influence this protein’s blood levels. However, if you’re taking medications (e.g., certain antibiotics or steroids), inform your provider to avoid false interpretations.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy