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Hemoglobin Free Iron Concentration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of free (unbound) iron present in your blood serum. Free iron is a form of iron that can be absorbed by the body and may contribute to oxidative stress or iron overload conditions.

Quick summary

["Free iron levels help assess iron metabolism and potential risks of iron-related disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47309-0
Short code
Haem influ B IgG 2:1 Ser-Rto
Synonyms
Haem influ B IgG 2:1 Ser-Rto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, weakness, or signs of iron overload (such as organ damage). It may also be used to monitor iron status in patients with certain blood disorders, chronic diseases, or after treatments involving iron supplements or transfusions.

What to Expect Before the Test

No special preparation is typically needed. You may have a small needle inserted into your arm to draw blood. If you’re on iron supplements, ask your provider whether to stop them temporarily, as this could affect results.

What the Results Mean

Results are not provided with specific reference ranges, as iron levels can vary based on factors like diet, health conditions, and medications. Your provider will interpret the result in the context of your overall health and medical history.

Common Conditions Linked to Free Iron Levels

Elevated free iron may be linked to conditions like hemochromatosis (iron overload) or certain cancers. Low levels could indicate iron deficiency or other metabolic issues. Always discuss results with your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Free Iron in Serum

Frequently asked questions

How is this test used in diagnosis or treatment planning?
This test helps identify whether free iron is abnormally high or low, which can guide decisions about iron therapy, monitoring for iron-related diseases, or evaluating responses to treatments.
What does an abnormal result mean?
An abnormal result may signal an underlying condition requiring further evaluation by your healthcare provider, such as genetic disorders, chronic diseases, or exposure to iron-containing substances.
Can diet or medications affect this test?
Yes, iron-rich foods, supplements, or certain medications (e.g., blood thinners) can influence iron levels. Always inform your provider about all medications or dietary changes before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy