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Hantavirus IgG Antibody (Serum/Plasma) – Qualitative Line Blot Assay

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the hantavirus, a group of viruses that can cause severe respiratory illness in humans. It helps determine if your immune system has previously encountered the virus.

Quick summary

["This test checks for past exposure to hantavirus, not active infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101209-5
Short code
Hantavirus IgG panel SerPl Line blot
Synonyms
Hantavirus IgG panel SerPl Line blot
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a line blot immunoassay to identify specific antibodies (IgG) against hantavirus proteins in your blood. These antibodies are produced by your immune system in response to past infection, but not during an active illness. The presence of these antibodies suggests exposure to the virus at some point, though symptoms may not have occurred.

Why It Might Be Ordered

Your healthcare provider may order this test if you’ve had recent exposure to rodents (common carriers of hantavirus), have symptoms of hantavirus pulmonary syndrome (such as fever, cough, or difficulty breathing) after exposure, or if you’re part of a research study investigating hantavirus risk.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (either serum or plasma) via venipuncture. If you’re concerned about needle phobia, let your lab technician know so they can take steps to make it more comfortable.

What to Expect After the Test

Results are typically qualitative (positive or negative) and may take several days to weeks to receive. If positive, further testing may be needed to confirm exposure timing or rule out other conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive IgG result indicates past exposure to hantavirus, meaning your body has mounted an immune response. However, this does not guarantee you were sick or that you’re currently infected. If you’ve had symptoms after exposure, active testing (such as PCR or IgM assays) may be needed to diagnose current illness. A negative result means no detectable antibodies were found, suggesting either no prior exposure or insufficient time for antibody development.

Short name

Hantavirus IgG Antibody (Line Blot)

Frequently asked questions

Will this test show if I currently have hantavirus?
No. This test only detects antibodies produced after past exposure. For active infection, additional tests like PCR (to detect viral RNA) or IgM antibody testing would be needed.
How soon after exposure can I expect results?
Results may take days to weeks, depending on your healthcare provider’s lab. Antibodies typically develop within weeks to months after exposure, so timing of results can vary widely.
Can I get this test at home?
No. This test requires a blood sample collected in a clinical setting by a trained healthcare professional.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy