High-Sensitivity C-Reactive Protein (hs-CRP) in Serum

Why Is This Test Done?

Your doctor may order hs-CRP to evaluate your risk for cardiovascular conditions, such as heart attacks or strokes, especially if you have risk factors like high blood pressure, diabetes, or a family history of heart disease. It can also help monitor chronic inflammatory conditions like rheumatoid arthritis or certain infections.

What Does a High or Low Result Mean?

A higher-than-normal hs-CRP level suggests increased inflammation in your body, which may raise the risk of heart disease. A lower level generally indicates lower inflammation. However, results alone don’t diagnose a specific condition—your doctor will consider your overall health and other test results.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum (the liquid part after clotting), and the hs-CRP protein is measured using a sensitive immunoassay method.

What Are Common Causes of Abnormal Results?

Increased hs-CRP levels can occur with infections, injuries, autoimmune diseases, or other inflammatory processes. Smoking, obesity, stress, and certain medications may also affect results. Low levels might be normal or could indicate very mild inflammation.