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Total IgE (Immunoglobulin E) Antibody Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to certain parasites.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39543-4
Short code
Hazelnut IgE/IgE total %
Synonyms
Hazelnut IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgE Measure?

IgE (Immunoglobulin E) is a protein produced by your immune system in response to allergens, parasites, or infections. High levels of IgE can indicate allergies, asthma, or other immune-related conditions.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that suggest allergies. It can also help diagnose conditions like allergic asthma or certain parasitic infections.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using an immunoassay method to measure IgE levels.

What Do Results Mean?

Results are interpreted based on your symptoms and medical history. Elevated IgE levels may suggest an allergic reaction or immune response, while normal levels do not definitively rule out allergies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: IgE levels are critical in diagnosing allergic conditions, such as hay fever, eczema, or food allergies. They can also help assess immune responses to infections or other conditions affecting the immune system.

Short name

IgE Total

Frequently asked questions

What causes high IgE levels?
High IgE levels are often linked to allergies, asthma, or parasitic infections. Other conditions, like certain autoimmune diseases or chronic inflammatory disorders, may also be associated with elevated IgE.
What are the normal IgE levels?
There are no strict normal ranges for IgE levels alone, as they vary widely among individuals. Results are usually compared to your symptoms and medical context rather than a single reference range.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, infections, or other factors affecting your immune system. Regular monitoring may be needed if you have ongoing symptoms or conditions requiring management.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy