Hemoglobin A1c (HbA1c) with additional qualitative screening for hemoglobin variants (A1a, A1b, and deletion variants)
This test measures your long-term blood sugar levels and checks for specific types of hemoglobin variants that may affect how your blood sugar is managed.
["Helps monitor diabetes and identify unusual blood protein changes that could impact health."]
Key facts at a glance
- LOINC
- 103844-7
- Short code
- HBA1 + HBA2 Del Amn/CVS
- Synonyms
- HBA1 + HBA2 Del Amn/CVS
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Blood Sugar Control
HbA1c reflects your average blood sugar levels over the past 2–3 months by measuring the percentage of hemoglobin that has sugar molecules attached. This test is crucial for diagnosing and managing diabetes, as it provides a more stable picture than checking blood sugar at random times. Variations in hemoglobin types (like A1a, A1b, or deletions) may indicate genetic conditions or other health factors that could influence how your body processes glucose.
How the Test Works: Analyzing Blood Components
Your blood sample is analyzed using advanced techniques to separate and identify different hemoglobin types. The primary measurement (HbA1c) is done through an immunoassay method, while additional qualitative screening detects specific hemoglobin variants. This dual approach helps ensure accurate diagnosis and tailored treatment plans.
What to Expect Before and After the Test
No special preparation is needed for this test. You’ll have a small blood draw, similar to other routine lab tests. Results are typically ready within a few days. If variants are found, your healthcare provider may recommend further testing or genetic counseling.
Common Reasons for This Test
Doctors order this test to monitor diabetes, check for hereditary blood disorders, or evaluate unexplained symptoms like fatigue or anemia. It’s also used in newborn screening for conditions like sickle cell disease or thalassemia.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HbA1c Variant Screening
Frequently asked questions
What does an abnormal HbA1c or variant result mean?
Will I need to take any special steps if my results are abnormal?
Can I fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy