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Hemoglobin A1c (HbA1c) and Hemoglobin F (HbF) with Full Genetic Mutation Analysis (LAM)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood sugar levels over time (HbA1c) and checks for the presence of fetal hemoglobin (HbF), along with genetic analysis to identify specific mutations in hemoglobin-related genes.

Quick summary

["Helps monitor diabetes management and assess genetic risks for blood-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
102091-6
Short code
HBA1 + HBA2 Full Mut Anl Amn/CVS
Synonyms
HBA1 + HBA2 Full Mut Anl Amn/CVS
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What HbA1c Measures

HbA1c reflects your average blood sugar levels over the past 2–3 months, linked to your diabetes management. It’s a key tool for doctors to assess long-term glucose control.

Why HbF Is Tested

HbF is a type of hemoglobin found in fetal blood. In adults, its presence can indicate conditions like sickle cell trait or certain blood disorders. This test checks for its levels.

Genetic Mutation Analysis Overview

This part of the test examines DNA for specific mutations in genes involved in hemoglobin production. These mutations may affect blood health or predispose you to conditions like thalassemia or sickle cell disease.

How This Test Helps Your Doctor

Combining HbA1c, HbF, and genetic insights provides a fuller picture of your blood health. It helps tailor treatments for diabetes, manage genetic risks, and guide decisions about future care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c/HbF + Genetic Test

Frequently asked questions

Why would my doctor order this test?
Your doctor may recommend this test if you have diabetes, suspect a blood disorder, or have a family history of hemoglobin-related conditions. It helps monitor long-term blood sugar control and assess genetic risks.
What does an abnormal HbA1c result mean?
An elevated HbA1c suggests poor blood sugar control, which may require adjustments to diet, medication, or lifestyle. An abnormal HbF level or genetic mutation may point to conditions like sickle cell trait or thalassemia, needing further evaluation.
How long does it take to get results?
Results for HbA1c and HbF typically return within 1–2 weeks. Genetic mutation analysis may take longer, often 3–6 weeks, depending on lab processing times.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy