Hepatitis B Core Antibody, Qualitative (Serum/Plasma)
This test checks for the presence of antibodies against the hepatitis B core antigen in your blood, helping determine past or current hepatitis B infection status.
["This test helps assess whether you’ve been exposed to hepatitis B virus (HBV)."]
Key facts at a glance
- LOINC
- 109333-5
- Short code
- HBV core Ab Msmt Ser
- Synonyms
- HBV core Ab Msmt Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). Antibodies to the core protein of HBV can indicate exposure to the virus. This test is often used to diagnose past infection, screen for chronic infection, or evaluate immune response after vaccination.
How the Test Works
The test uses an immunoassay (a lab method that detects specific antibodies) to detect your body’s immune response to HBV. If antibodies are present, it suggests your immune system has recognized and fought the virus.
When You Might Need This Test
Your doctor may recommend this test if you have risk factors for hepatitis B (e.g., travel to high-risk regions, exposure to infected blood, or history of tattoos/injections), if you’re vaccinated but still want to check for infection, or if you’re evaluating chronic liver disease.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw a blood sample. The test is quick and usually done in a doctor’s office or lab.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results (antibodies detected) may indicate past infection, immunity from vaccination, or chronic infection requiring further evaluation. Negative results suggest no current infection or immunity. This test is critical for monitoring high-risk individuals and guiding treatment decisions.
Short name
HBV Core Antibody (Qualitative)
Frequently asked questions
What does a positive result mean?
Can this test detect acute or chronic hepatitis B?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy