Hepatitis B Core Antibody, Serum (Qualitative)
This test checks for antibodies to the hepatitis B core antigen in your blood. Antibodies are your body’s natural defense against viruses, including hepatitis B.
["This test helps determine if your immune system has ever been exposed to hepatitis B virus (HBV)."]
Key facts at a glance
- LOINC
- 16933-4
- Short code
- HBV core Ab Ser Ql
- Synonyms
- HBV core Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of hepatitis B core antibodies (HBcAb) in your serum. These antibodies appear after your body has encountered the hepatitis B virus, either through infection or vaccination. The test is qualitative, meaning it only tells you whether antibodies are present or not, not their exact amount.
Why It’s Done
Doctors may order this test if you have risk factors for hepatitis B, such as exposure to the virus (e.g., unprotected sex, sharing needles, or household contact with an infected person), or if you’re part of a group at higher risk (e.g., certain ethnicities, healthcare workers). It can also be used to screen before certain procedures or vaccinations.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you can return to your normal activities afterward.
What the Results Mean
If the test is positive, it means your body has produced antibodies against hepatitis B core antigen, suggesting past or possible current infection. A negative result means no detectable antibodies were found, indicating either no exposure or immunity from vaccination.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Hepatitis B Core Antibody (HBcAb) Test
Frequently asked questions
What does a positive result mean?
Can this test be used to diagnose active hepatitis B?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy