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Hepatitis B Core Antibody, Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the hepatitis B core antigen in your blood. Antibodies are your body’s natural defense against viruses, including hepatitis B.

Quick summary

["This test helps determine if your immune system has ever been exposed to hepatitis B virus (HBV)."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16933-4
Short code
HBV core Ab Ser Ql
Synonyms
HBV core Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of hepatitis B core antibodies (HBcAb) in your serum. These antibodies appear after your body has encountered the hepatitis B virus, either through infection or vaccination. The test is qualitative, meaning it only tells you whether antibodies are present or not, not their exact amount.

Why It’s Done

Doctors may order this test if you have risk factors for hepatitis B, such as exposure to the virus (e.g., unprotected sex, sharing needles, or household contact with an infected person), or if you’re part of a group at higher risk (e.g., certain ethnicities, healthcare workers). It can also be used to screen before certain procedures or vaccinations.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you can return to your normal activities afterward.

What the Results Mean

If the test is positive, it means your body has produced antibodies against hepatitis B core antigen, suggesting past or possible current infection. A negative result means no detectable antibodies were found, indicating either no exposure or immunity from vaccination.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hepatitis B Core Antibody (HBcAb) Test

Frequently asked questions

What does a positive result mean?
A positive result means your body has detected the hepatitis B core virus or antibodies to it, which could indicate past infection or current immunity. It does not always mean you are actively infected; further testing may be needed to clarify your status.
Can this test be used to diagnose active hepatitis B?
No, this test alone cannot diagnose active hepatitis B. It only shows if your body has ever been exposed to the virus. For active infection, your doctor may order additional tests, such as hepatitis B surface antigen (HBsAg) or hepatitis B e antigen (HBeAg) tests.
Is this test covered by insurance?
Whether this test is covered by insurance depends on your specific plan, medical reason for testing, and local healthcare policies. Always confirm with your insurance provider or healthcare provider before scheduling the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy