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Hepatitis B Core Antibody, Qualitative (IgM)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of Hepatitis B Core Antibody IgM, an immune marker that can indicate an active hepatitis B virus (HBV) infection.

Quick summary

["IgM antibodies may signal recent or ongoing HBV infection; IgG antibodies suggest past infection or immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51658-3
Short code
HBV core IgM Fld Ql
Synonyms
HBV core IgM Fld Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The Hepatitis B Core Antibody IgM test identifies a specific type of antibody (IgM) produced by your immune system in response to the Hepatitis B virus. IgM antibodies typically appear early in an infection and can help doctors determine if you have an active HBV infection rather than a past one.

Why It’s Done

Your healthcare provider may order this test if you have symptoms of hepatitis (such as fatigue, jaundice, or abdominal pain), if you’ve been exposed to HBV, or as part of routine screening for certain groups at higher risk (e.g., healthcare workers, travelers to high-risk areas). It can also be used to monitor treatment progress.

Sample Collection and Preparation

This test uses a blood sample, though the exact fluid type (serum/plasma) may vary. Blood is drawn from a vein, typically in your arm, and sent to a lab for analysis. Results are qualitative (yes/no) rather than a numerical value.

Interpreting Your Results

A positive IgM result suggests an active HBV infection. A negative result means you either have no infection or a past infection with resolved IgM antibodies. Follow-up testing (e.g., for IgG antibodies or viral load) may be needed to clarify the situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HBc IgM Antibody

Frequently asked questions

What Does a Positive Result Mean?
A positive IgM result indicates you likely have an active HBV infection. This means the virus is currently replicating in your body, and you should consult your doctor about next steps, which may include antiviral treatment, monitoring, or vaccination if you’re unvaccinated.
What Does a Negative Result Mean?
A negative IgM result means you either do not have an active HBV infection or your body has cleared the virus (with IgM antibodies no longer present). However, you may still have past exposure or immunity. Your doctor may recommend additional tests (e.g., for Hepatitis B surface antibody or viral load) to confirm this.
Can This Test Be Used to Track Treatment Progress?
Yes, but indirectly. While this test doesn’t measure treatment response directly, a negative IgM result over time (alongside other markers like viral load) can suggest the virus is being controlled. Your doctor will likely use a combination of tests to monitor treatment effectiveness.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy