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Hepatitis B Core Antibody, Qualitative (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of IgM antibodies against the hepatitis B core antigen, which can indicate an active infection with hepatitis B virus (HBV). IgM antibodies typically appear early in infection and may help identify recent exposure.

Quick summary

["This test helps determine if you have an active hepatitis B infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108692-5
Short code
HBV core IgM Msmt SerPl
Synonyms
HBV core IgM Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures IgM antibodies produced by your immune system in response to the hepatitis B core antigen. These antibodies are often found during the early stages of hepatitis B infection, helping doctors distinguish between acute infection and other conditions.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of hepatitis B (such as fatigue, nausea, or jaundice), if you’ve been exposed to hepatitis B, or if you’re part of a screening for hepatitis B in certain groups (e.g., pregnant individuals, travelers to high-risk areas).

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. The process is quick and usually painless.

What to Expect After the Test

After the blood is drawn, you may experience mild bruising or soreness at the site. Apply gentle pressure to stop any bleeding. Rest for a short time if you felt dizzy or lightheaded during the procedure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Hepatitis B Core Antibody (IgM) Test

Frequently asked questions

Positive IgM antibodies suggest an active hepatitis B infection, meaning the virus is currently replicating in your body. This can be critical for early treatment and managing symptoms. However, IgM antibodies can also be present in rare cases of chronic hepatitis B if the infection was acquired early in life. Always consult your healthcare provider for interpretation.
This test alone does not diagnose hepatitis B definitively. Your doctor may also check for other markers, such as hepatitis B surface antibodies or hepatitis B surface antigen, to confirm the stage and type of infection.
If my test results are positive, what should I do next?
If your test shows IgM antibodies, your healthcare provider will likely recommend further testing to confirm the diagnosis and determine the best course of treatment. They may also check for hepatitis B surface antigen to see if the infection is active or resolved.
Can I get hepatitis B from this test?
No, this test involves only blood samples collected in a sterile environment. The risk of infection from the test itself is extremely low, as all medical facilities follow strict safety protocols to prevent contamination.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy