Hepatitis B Core Antibody, Serum (Qualitative Immunoassay)

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of hepatitis B, such as fatigue, nausea, abdominal pain, or jaundice. It may also be used to monitor people at higher risk of hepatitis B, like those with multiple sexual partners, intravenous drug users, or those with certain medical conditions. Sometimes, it’s part of a screening process for hepatitis B infection, especially in newborns or during pregnancy.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein in your arm to draw blood. The process usually takes a few minutes. If you’re pregnant, breastfeeding, or have a bleeding disorder, let your healthcare provider know before the test.

What Happens During the Test

Blood is collected from a vein in your arm using a needle. After the blood is drawn, a bandage will be applied to the area. The test involves analyzing the serum portion of your blood for specific antibodies that indicate an HBV infection.

What the Results Mean

Positive results mean you have antibodies against the hepatitis B core antigen, which may suggest you have been infected with hepatitis B virus in the past or currently. The presence of IgM antibodies specifically often indicates an acute (new) infection. Negative results mean no detectable antibodies were found in your blood sample.