Hepatitis B Core Antibody, IgM (Serum) – Confirmatory Test

What Does This Test Measure?

The test measures **IgM antibodies** specific to the hepatitis B virus core protein. These antibodies are produced by your immune system in response to an active infection. IgM is often the first antibody detected shortly after exposure to the virus.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of hepatitis B (e.g., fatigue, jaundice, abdominal pain) or if you’ve been exposed to the virus. It can also be used to monitor chronic hepatitis B cases or rule out recent infection in high-risk groups (e.g., travelers, healthcare workers).

What Does a Positive Result Mean?

A positive result suggests you are currently infected with hepatitis B, as IgM antibodies indicate an active immune response to the virus. This does not mean you will develop chronic liver disease, but it requires medical evaluation and treatment to manage the infection.

What Does a Negative Result Mean?

A negative result means your body either hasn’t been exposed to hepatitis B recently or has already cleared the infection (with IgM antibodies no longer present). However, chronic infection may still be present if other markers (e.g., surface antibodies) are elevated.