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Hemoglobin Variants by Probe (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal hemoglobin types in your blood, which may indicate conditions like sickle cell disease or other inherited blood disorders.

Quick summary

["This screening helps identify rare or unusual hemoglobin variants that could affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49364-3
Short code
HBV DNA # Mar NAA+probe
Synonyms
HBV DNA # Mar NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fatigue, pain, frequent infections, or if you have a family history of blood disorders. It’s also used in newborn screening or before certain medical procedures.

What to Expect Before the Test

No special preparation is needed. A small blood sample will be taken from your arm, similar to a routine blood draw. The test is usually done in a lab and results may take a few days.

What the Results Mean

Results show whether abnormal hemoglobin variants are present. If variants are found, further testing may be needed to determine the specific type and its impact on your health.

Common Conditions Linked to This Test

Positive results for certain hemoglobin variants may suggest conditions like sickle cell disease, thalassemia, or other inherited blood disorders. These conditions can affect how your blood carries oxygen and may require ongoing medical care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hb Variant Screening

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of abnormal hemoglobin variants. This could mean you have an inherited blood disorder like sickle cell disease or thalassemia, or another rare condition. Your doctor will discuss the next steps, which may include additional testing or monitoring.
How often should I get this test?
The frequency depends on your symptoms, medical history, and doctor’s recommendations. If you have a known blood disorder, your doctor may schedule regular follow-ups. If this is a one-time screening, results may not require repeat testing unless further evaluation is needed.
Can I prepare for this test at home?
No special preparation is needed. You may eat and drink normally before the test, but avoid heavy exercise or stressing your arm before the blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy