Hemoglobin Variants by Electrophoresis (Serum/Plasma)
This test measures different forms of hemoglobin, the protein in red blood cells that carries oxygen. Variations can help diagnose conditions like sickle cell disease or other inherited blood disorders.
["Identifying abnormal hemoglobin types may help pinpoint genetic or blood-related health concerns."]
Key facts at a glance
- LOINC
- 49602-6
- Short code
- HBV DNA Mar NAA+probe-Log IU
- Synonyms
- HBV DNA Mar NAA+probe-Log IU
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order this test if you have symptoms like fatigue, pain in bones or joints, or if family members have a history of blood disorders. It’s also used to screen for conditions like sickle cell trait or disease, especially in people of certain ethnic backgrounds.
How the Test Works
A small blood sample is taken and analyzed using electrophoresis, a method that separates hemoglobin variants based on their electrical charge. Different bands on the result indicate the presence of various hemoglobin types.
Sample Collection
Blood is drawn from a vein, usually in your arm, by a healthcare professional. You may feel a slight pinch, but it’s generally quick and not painful. You can eat or drink normally before the test.
What to Expect After the Test
After the blood draw, you’ll likely return to your regular activities immediately. There may be a small bruise or slight discomfort at the site, but it should resolve quickly. Results are typically available within a few days to a week, depending on lab processing times.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal hemoglobin variants can signal genetic disorders, such as sickle cell anemia or thalassemia. Detecting these variants early can guide treatment plans, including lifestyle changes, medications, or monitoring for complications. Some variants may also be harmless but warrant further investigation if they’re unexpected.
Short name
Hb Variants Electrophoresis
Frequently asked questions
How long does it take to get my results?
What does it mean if my test shows abnormal hemoglobin?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy