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Human Herpesvirus 8 (HHV-8) DNA in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of genetic material from Human Herpesvirus 8 (HHV-8), a virus linked to certain cancers and infections.

Quick summary

["It helps assess viral activity in your blood, which may be important for monitoring conditions like Kaposi sarcoma or certain lymphomas."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32686-8
Short code
HBV DNA Ser-mCnc
Synonyms
HBV DNA Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a history of conditions associated with HHV-8, such as Kaposi sarcoma, certain lymphomas, or persistent organomegaly syndrome. It may also be used during treatment to monitor viral load levels.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast before the draw, but this is often not required for viral DNA testing. Bring any medications or supplements you’re taking to your appointment.

How the Test Works

A blood sample is taken from a vein in your arm. The lab analyzes a small portion of your serum or plasma to detect and measure the genetic material (DNA) of HHV-8 using advanced laboratory techniques.

What the Results Mean

Results are typically reported as a viral load (amount of HHV-8 DNA present). Higher levels may indicate active viral infection, while lower or undetectable levels may suggest control or absence of active infection. Your healthcare provider will interpret the results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HHV-8 Viral Load

Frequently asked questions

How often will I need this test?
Your healthcare provider will determine how often you need this test based on your medical condition, treatment plan, and response to therapy. Some patients may need testing more frequently during active treatment or monitoring of viral load.
What are the possible side effects of this test?
The most common side effect is a mild bruise or slight discomfort at the needle insertion site. Rarely, there may be a slight swelling or redness. If you experience excessive pain or signs of infection (like fever or increased redness), contact your healthcare provider.
Can I still take my usual medications before the test?
Yes, you can typically continue taking your usual medications as directed. However, inform your healthcare provider or lab technician about any medications, supplements, or over-the-counter drugs you’re taking to ensure they don’t interfere with the test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy