Genetic test for hemoglobin variant status (specifically evaluating for sickle cell trait or related hemoglobinopathies via DNA sequencing)
This test checks your DNA to identify certain inherited blood conditions, such as sickle cell trait, which may affect how your red blood cells function.
["Helps determine if you carry genetic mutations linked to blood disorders that could influence health risks or treatment options."]
Key facts at a glance
- LOINC
- 61169-9
- Short code
- HBV I233V Islt Ql Genotyp
- Synonyms
- HBV I233V Islt Ql Genotyp
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- genotyping
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test analyzes your DNA to detect specific changes (mutations) in the genes responsible for producing hemoglobin, the protein in red blood cells that carries oxygen. It identifies variants that may lead to conditions like sickle cell disease or sickle cell trait.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have a family history of sickle cell disease, are planning pregnancy, or have symptoms like fatigue, pain, or frequent infections that could relate to blood disorders.
Common Uses in Healthcare
Used for prenatal screening, preconception counseling, and diagnosing or confirming inherited blood disorders in adults and children. Helps guide decisions about pregnancy planning, medical management, and genetic counseling.
What to Expect Before the Test
No special preparation is needed. A small blood sample is taken from your arm, similar to a regular blood draw. If you’re pregnant, you may be asked to provide a sample from your placenta or amniotic fluid during pregnancy testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Identifying hemoglobin variants can help prevent complications, such as severe pain crises, infections, or organ damage associated with sickle cell disease. It also supports personalized medical care, including monitoring during pregnancy and managing symptoms with targeted therapies.
Short name
Hemoglobin variant genetic test
Frequently asked questions
Will this test show if I have sickle cell disease?
How long will it take to get results?
Can I get this test if I’m not pregnant?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy