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Genetic test for hemoglobin variant screening (qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal types of hemoglobin, the protein in red blood cells that carries oxygen. Certain variants can cause health issues like anemia or blood disorders.

Quick summary

["Helps identify inherited blood conditions linked to abnormal hemoglobin."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61171-5
Short code
HBV M250I Islt Ql Genotyp
Synonyms
HBV M250I Islt Ql Genotyp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
genotyping
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

This test detects specific genetic mutations that alter the structure of hemoglobin, which may lead to conditions like sickle cell disease or thalassemia. It looks for qualitative differences in hemoglobin types rather than precise concentrations.

Why Might You Need This Test?

Your doctor may recommend this test if you have a family history of hemoglobin disorders, certain blood-related symptoms, or if you’re pregnant and at risk for complications.

How Is the Test Performed?

A small blood sample is taken from your arm. The sample is then analyzed to identify any genetic variants in hemoglobin production.

What Are the Next Steps?

Results may guide further testing, such as additional genetic analysis or monitoring for symptoms. Follow-up care depends on your doctor’s recommendations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin variant screening

Frequently asked questions

Why was I asked to take this test?
Your doctor may suspect a hemoglobin variant based on your medical history, symptoms, or family history of blood disorders. This test helps confirm or rule out certain conditions.
What do my results mean?
Results may indicate a normal variant, a known condition (like sickle cell trait), or an unknown variant that may require further genetic testing. Always discuss results with your healthcare provider.
Can I fast before this test?
No fasting is required for this blood test. However, follow any specific instructions your lab provides for optimal results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy