Hemoglobin Variants by Surface Immunoglobulin Screening (Serum)
This test helps identify unusual or abnormal forms of hemoglobin, which may be linked to conditions like sickle cell disease or other inherited blood disorders.
["This screening can help diagnose rare blood disorders affecting red blood cells."]
Key facts at a glance
- LOINC
- 49177-9
- Short code
- HBV surface IgG Ser Ql
- Synonyms
- HBV surface IgG Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects variations in hemoglobin structure using a surface immunoglobulin-based method. Hemoglobin is the protein in red blood cells that carries oxygen. Variations can occur due to genetic mutations or other factors, and some may cause health issues like anemia or blood clots.
Why It’s Ordered
Your healthcare provider may order this test if you have symptoms like fatigue, pain, frequent infections, or if you have a family history of hemoglobin disorders. It can also be part of prenatal screening for genetic conditions.
Common Conditions Linked to This Test
Abnormal hemoglobin variants may be associated with conditions such as sickle cell disease, thalassemia, or other inherited blood disorders. Some variants may not cause symptoms until later in life.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample from a vein, usually in a clinic or lab. The process takes a few minutes, and you can resume normal activities afterward.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Identifying hemoglobin variants early can guide treatment decisions, such as managing pain, preventing infections, or planning pregnancy. Some variants may require monitoring or specialized care, while others may not need intervention.
Short name
Hemoglobin Variant Screen (Serum)
Frequently asked questions
How long does it take to get results?
What does a positive result mean?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy