Skip to content

Serum IgG Immunoglobulin Level (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), the most common type of antibody in your blood. IgG helps fight infections and is important for long-term immunity.

Quick summary

["IgG antibodies protect your body against infections and diseases over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109973-8
Short code
H capsul IgA Msmt Ser
Synonyms
H capsul IgA Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is the primary antibody your immune system produces to defend against bacteria, viruses, and toxins. It circulates in your bloodstream and provides long-lasting protection. This test helps doctors assess your immune response, check for infections, or evaluate conditions like immune deficiencies or autoimmune diseases.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of infection, if you’re recovering from an illness, or if you have a condition that affects your immune system, such as HIV, lupus, or certain cancers. It can also be used to monitor treatment responses or diagnose immune-related disorders.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. The process usually takes a few minutes, and you can resume normal activities afterward.

What to Expect During the Test

The blood sample is sent to a lab where it is analyzed to measure IgG levels. The results are typically ready within a few days, depending on lab processing times.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG levels can vary based on infections, immune responses, age, and underlying health conditions. Low IgG levels may indicate an immune deficiency, while very high levels could suggest chronic infections or certain immune disorders. Always discuss your results with your healthcare provider for personalized interpretation.

Short name

IgG Level

Frequently asked questions

When could my IgG levels be checked?
Your IgG levels may be checked if you have symptoms like frequent infections, fatigue, or unexplained weight loss. It’s also used in monitoring conditions like HIV, autoimmune diseases, or after receiving immune-boosting treatments.
What do my IgG results mean?
Results are compared to a general reference range, but they depend on your health, age, and medical history. Your doctor will explain what your specific results mean in the context of your overall health.
Can IgG levels change over time?
Yes, IgG levels can fluctuate due to infections, vaccinations, or medical treatments. Regular monitoring may be needed if you have a chronic condition affecting your immune system.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy