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Human Chorionic Gonadotropin (HCG) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of human chorionic gonadotropin (HCG), a hormone produced during pregnancy. It helps confirm pregnancy or detect certain conditions like ectopic pregnancy or gestational trophoblastic disease.

Quick summary

["HCG levels can indicate pregnancy or other health concerns; results guide further medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42891-2
Short code
HCG Fld-aCnc
Synonyms
HCG Fld-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HCG Used For?

HCG is primarily used to confirm pregnancy, especially in early stages when other tests may not be reliable. It can also help monitor high-risk pregnancies or detect complications like miscarriage or ectopic pregnancies. Doctors may also use HCG to evaluate conditions such as gestational trophoblastic disease (a rare pregnancy complication).

How Is the HCG Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to detect HCG levels. Sometimes, urine samples may be tested for HCG, but blood tests are more accurate for early pregnancy detection.

When Might You Need an HCG Test?

You may need an HCG test if you suspect you are pregnant, especially if you missed a period or have other pregnancy symptoms. Doctors may also order it during pregnancy monitoring, after a miscarriage or ectopic pregnancy diagnosis, or in cases of suspected gestational trophoblastic disease.

What Do HCG Results Mean?

HCG levels rise steadily during early pregnancy, typically doubling every 48–72 hours. If you are pregnant, your HCG levels should increase over time. Abnormally low or rapidly declining levels may signal complications. Your doctor will interpret results in the context of your medical history and symptoms.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HCG Test

Frequently asked questions

Why might my HCG levels be checked if I’m not pregnant?
If you’re not pregnant, abnormal HCG levels could be due to conditions like ovarian cysts, certain cancers (e.g., testicular cancer in men), or other hormonal imbalances. Your doctor will discuss findings with you based on your symptoms and medical history.
What if my HCG levels are very high?
Very high HCG levels in a non-pregnant person may require further evaluation to rule out conditions like gestational trophoblastic disease or other rare disorders. Your doctor will guide you on next steps, which may include additional tests or monitoring.
Can HCG levels be affected by medications?
Some medications, such as certain fertility treatments or hormonal drugs, may influence HCG levels. If you’re taking medications, let your healthcare provider know before testing, as this may impact results or interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy