Skip to content

Intact Human Chorionic Gonadotropin (hCG) — Serum/Plasma or Whole Blood, Rapid Immunoassay, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures intact hCG in blood to help determine pregnancy; the specimen and reporting format depend on the test used.

Quick summary

["Detectable hCG usually supports a pregnancy diagnosis, but early testing and the clinical context can affect the result."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106737-0
Short code
HCG Intact+B SerPlBld IA.rapid-mCnc
Synonyms
HCG Intact+B SerPlBld IA.rapid-mCnc
Category
kidney
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures intact human chorionic gonadotropin, or hCG, in serum, plasma, or whole blood. hCG is a hormone produced by the placenta after implantation and is the hormone detected by most pregnancy tests.

Why might I need this test?

The test is commonly used to confirm or rule out pregnancy. It may also be used to follow hCG levels over time when a clinician needs to assess pregnancy progression or investigate certain nonpregnancy conditions.

How is the test performed?

A blood sample is analyzed with a rapid immunoassay, which detects hCG using antibodies. Depending on the laboratory method, the result may be reported as present or absent, as an amount per unit of blood volume, or both.

How do I prepare for the test?

Special preparation is usually not required for a blood hCG test. If serial measurements are ordered, testing at consistent times and recording all results can help your clinician interpret the trend.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detectable hCG in a patient who may be pregnant generally supports the diagnosis of pregnancy. A negative result does not always exclude pregnancy because hCG may be too low to detect very early, particularly soon after a missed period. Unexpectedly high or changing values may prompt repeat testing or further evaluation by a clinician.

Short name

Intact hCG test

Frequently asked questions

Does a positive hCG result always mean I am pregnant?
A positive result usually indicates pregnancy, but your clinician should interpret it with your symptoms, menstrual history, and other test results. Very rarely, hCG can be detected outside pregnancy.
Why might my hCG test be negative even though I might be pregnant?
Testing may have occurred too early for hCG to reach a detectable level, or the sample or assay may not have detected it. Repeating the test after a short interval can be appropriate if your clinician recommends it.
Why are multiple hCG results sometimes checked?
Clinicians may compare repeated values to evaluate how pregnancy-related hCG is changing. The appropriate timing and interpretation depend on the clinical situation and the laboratory's reporting method.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy