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Human Chorionic Gonadotropin (hCG) Quantitative Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of human chorionic gonadotropin (hCG), a hormone produced after pregnancy begins, typically detected in early pregnancy. It helps confirm pregnancy and monitor conditions like ectopic pregnancy or molar pregnancy.

Quick summary

["The hCG test is crucial for early pregnancy confirmation and certain medical evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108767-5
Short code
HCG Intact Msmt SerPl
Synonyms
HCG Intact Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Human Chorionic Gonadotropin (hCG)?

hCG is a hormone produced by the placenta shortly after fertilization. It signals the body that a pregnancy is developing and is essential for maintaining early pregnancy. Levels rise steadily during normal pregnancy and can be detected in blood or urine.

How Is This Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to measure hCG concentration. Urine tests can also detect hCG but are less precise for early pregnancy confirmation.

When Might You Need This Test?

Your healthcare provider may order an hCG test if you suspect pregnancy, experience unusual symptoms (e.g., severe nausea, missed periods), or are being evaluated for conditions like ectopic pregnancy, molar pregnancy, or certain cancers.

What Are Common Uses?

Common reasons include confirming pregnancy, assessing viability, diagnosing ectopic pregnancies, monitoring high-risk pregnancies, or evaluating symptoms of hCG-producing tumors.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hCG Level

Frequently asked questions

Why do some people need multiple hCG tests?
Your provider may recommend multiple tests to monitor changes in hCG levels over time. For example, in early pregnancy, hCG doubles roughly every 48–72 hours, which helps assess how the pregnancy is progressing.
What do abnormal hCG levels mean?
Abnormally low or irregular hCG levels can signal problems like a failed pregnancy, ectopic pregnancy, or conditions affecting hormone production. High levels in non-pregnant individuals may indicate certain cancers.
Can diet or supplements affect hCG test results?
No, hCG is produced by the placenta and is not influenced by diet or supplements. However, certain medications (e.g., some hormonal treatments) may be avoided before testing to prevent interference.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy