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Human Chorionic Gonadotropin (hCG) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of human chorionic gonadotropin (hCG), a hormone produced during pregnancy. It helps confirm pregnancy or evaluate conditions that may cause abnormal hCG levels.

Quick summary

["hCG is key for pregnancy diagnosis and monitoring certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2118-8
Short code
HCG SerPl Ql
Synonyms
HCG SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84702
SNOMED
275917004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order an hCG test to check for pregnancy, especially if you have missed periods, unusual vaginal bleeding, or symptoms like nausea or breast tenderness. It can also be used to monitor early pregnancy or detect conditions like ectopic pregnancy, molar pregnancy, or certain cancers (e.g., testicular or ovarian).

What Does a High or Low hCG Level Mean?

High levels of hCG are most commonly associated with pregnancy. However, very high levels can sometimes indicate complications like molar pregnancy. Low levels may suggest early pregnancy loss, a non-pregnant state, or certain medical conditions. Always discuss results with your healthcare provider.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is sent to a lab where it is tested for hCG levels using an immunoassay method. This process usually takes a few hours to complete.

What Should You Expect Before the Test?

No special preparation is needed for this test. You can eat, drink, or take medications as usual. If you are pregnant, inform your healthcare provider before the test.

Reference range

Non-pregnant: <5 mIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

hCG levels are critical in pregnancy diagnosis and monitoring. In early pregnancy, hCG levels rise steadily and can help confirm a viable pregnancy. Abnormal levels may indicate issues such as miscarriage, ectopic pregnancy, or molar pregnancy. Outside of pregnancy, elevated hCG can be linked to certain cancers, though this is rare. Low levels may signal conditions like early pregnancy failure or non-pregnant states.

Short name

hCG Serum/Plasma

Frequently asked questions

What Are the Normal Ranges?
There are no specific 'normal' ranges provided here because reference intervals can vary by lab and pregnancy stage. Your healthcare provider will interpret the results in the context of your symptoms, medical history, and other tests.
How Often Should I Get This Test?
The frequency depends on your situation. If you are pregnant, your doctor may recommend retesting hCG levels at specific intervals (e.g., every few days) to monitor progression. For non-pregnant individuals or those with suspected conditions, your doctor will determine the timing based on clinical needs.
Can I Take Anything Before the Test?
No, you should avoid fasting unless instructed by your healthcare provider. Follow their guidance to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy