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Bicarbonate concentration in dialysate fluid (measured via substance concentration method)

Published: August 9, 2026Updated: August 17, 2026

This test measures the bicarbonate level in the fluid used during dialysis, helping doctors monitor how well your kidneys are being supported during treatment.

Quick summary

["This test assesses bicarbonate balance in dialysis fluid, critical for maintaining acid-base balance during kidney dialysis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
12514-6
Short code
HCO3 Dial fld-sCnc
Synonyms
HCO3 Dial fld-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
28
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Bicarbonate is a key chemical in your body that helps balance acidity (pH). During dialysis, the dialysate fluid removes waste and excess acid from your blood. This test checks how much bicarbonate is present in that fluid to ensure it’s working properly to support your body’s pH balance.

Why Might You Need This Test?

Doctors may order this test if you’re on dialysis to verify that the dialysate fluid is correctly formulated to prevent metabolic imbalances, such as too much or too little acid in your blood.

How Is the Sample Collected?

A sample of dialysate fluid is collected from your dialysis machine during treatment. This fluid is already processed and used to clean your blood, so no additional blood draw is needed for this test.

What Does the Result Mean?

Results help healthcare providers adjust the dialysate solution if needed to maintain proper bicarbonate levels, which can affect your overall health and how well your dialysis is working.

Reference range

NCBI: HCO3- 22-28 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Dialysate bicarbonate level

Frequently asked questions

Why would my dialysate bicarbonate level be checked regularly?
Regular checks help ensure your dialysis treatment is supporting your body’s natural pH balance, preventing long-term health risks from acid-base imbalances.
What could cause a low or high bicarbonate level in the dialysate?
Possible causes include incorrect dialysate formulation, improper dialysis settings, or underlying conditions affecting fluid balance. Your doctor will review your results with you.
Does this test require fasting or special preparation?
No special preparation is needed. The sample is taken during dialysis, so no dietary or timing restrictions apply.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy